May/June 2023 Vol 29.4Therapeutic Use of Trace Elements in Dermatology
Authors: Anita Gade DO, Karl Hoegler MD, Jacqueline R Hwang BS, Amor Khachemoune MD, Samiya Khan BS
Abstract:
Trace elements (microminerals) play a role in many physiological functions, including hormone production and cellular growth. However, their importance in diagnosing and treating dermatologic disease has not been well examined. In this review, we discuss the functions, sources, and recommended requirements of each micromineral. In addition, we analyze the systemic and dermatological manifestations associated with micromineral imbalances. The pathogenesis of genodermatoses, such as Wilson disease, Menkes disease, acrodermatitis enteropathica, and allergic dermatitis, are also discussed. Included are studies examining the potential therapeutic role of zinc, selenium, and copper in inflammatory diseases, skin cancer, and photoaging.
