September/October 2026 Vol 32.5Dermatological Promise of Pomegranate in Hyperpigmentation and Skin Aging
Authors: Maleeha Ahmad BS, Zaryab Alam BS, Lanah Almatroud BA, Amor Khachemoune MD
Abstract:
Background • Punica granatum, commonly known as pomegranate, is highly regarded for its diverse uses, including as a flavorful fruit, a natural dye, and an integral component of Middle Eastern and South Asian cultural practices. In addition to its historical significance, pomegranate has demonstrated therapeutic value in treating various conditions, such as breast cancer, ischemic heart disease, and metabolic syndrome.
Aim • This review, however, specifically explores the dermatological applications of pomegranate.
Method • A comprehensive narrative review was conducted, with the search terms “pomegranate,” “dermatology,” and “skin.” Forty-three relevant studies were identified, with only those directly assessing pomegranate-based products included in the analysis.
Results • Our findings indicate that pomegranate peel exhibits significant potential in alleviating hyperpigmentation, as supported by controlled studies, while whole pomegranate extract and pomegranate seed oil show greater efficacy in mitigating skin aging and combating skin cancers, respectively.
Conclusion • This review highlights the pharmacological effects of various pomegranate components, including seeds, fruit, and peel, in the treatment of hyperpigmentation, skin aging, and skin cancer. However, further studies are warranted to ascertain optimal usage, including dosage and formulation.
