April/May 2026 Vol 25.2Functional Medicine Research in Clinical Practice: A Call to Action for Practitioners
Authors: Christopher R. D’Adamo PhD, Michelle Harreld MS, Michael B. Kaplan ND, Maia Kurnik MPH, RD, ACSM-EP, Amy R. Mack MSES/MPA, Joseph Pizzorno ND
Abstract:
Functional medicine–trained practitioners have conducted millions of patient care encounters worldwide. Many of these patients experience profound improvements in their health and wellbeing, and there is a growing evidence base that demonstrates the effectiveness of functional medicine.1-6 However, the majority of these improvements in patient outcomes are not yet being systematically documented, analyzed, and disseminated.
While there is abundant evidence in support of individual modalities used by functional medicine practitioners, more outcomes data from research that evaluates the comprehensive care model serves to further influence policymakers, insurers, and governing agencies to promote change in the healthcare system. Furthermore, the increasing acceptance of practice-based real-world evidence7,8 presents a timely opportunity for practitioners to conduct research in their practices to further expand the functional medicine evidence base.
